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Kanadaptin polyclonal antibody

Product Specifications

Background

HLC-3 is a 796 amino acid protein that is widely expressed in many tissues, including kidney, lung, liver, brain and skeletal and cardiac muscle. SLC4A1AP is a multidomain protein that localizes to the nucleus where it may play a role in signaling. SLC4A1AP was previously thought to act as an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane. However, recent studies suggest SLC4A1AP does not interact with kAE1. The gene encoding SLC4A1AP maps to chromosome 2, which consists of 237 million bases and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

Kanadaptin; Human lung cancer oncogene 3 protein; HLC-3; Kidney anion exchanger adapter protein; Solute carrier family 4 anion exchanger member 1 adapter protein

Swiss Prot

Q9BWU0

Reactivity

Human, Mouse, Rat

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Kanadaptin. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 88 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of Kanadaptin protein.

Applications Notes

Western blot analysis of Kanadaptin expression in mouse testis (A) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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