CD155 polyclonal antibody
Product Specifications
Background
Poliovirus receptor (PVR, CD155) is an immunoglobulin-like, transmembrane glycoprotein originally described as a mediator of poliovirus attachment to cells and later identified as important in adherens junction formation. Also known as nectin-like 5 (Necl-5), PVR binds nectin-3 and interacts with integrin αvβ3 and PDGFR to regulate integrin clustering and focal contact formation at the leading edge of migrating cells. Research studies demonstrate that PVR and nectin-3 regulate contact inhibition during cell motility and proliferation in transformed 3T3 cells. Additional research indicates that PVR (CD155, Necl-5) expression may play a role in invasiveness of lung adenocarcinoma. In the immune system, CD155 plays a role in natural killer (NK) cell-mediated cytotoxicity.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Poliovirus receptor; Nectin-like protein 5 (NECL-5) ; CD155; PVR; PVS
Swiss Prot
P15151
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to Human CD155.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:5000~1:10000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD155 polyclonal antibody detects endogenous levels of CD155 protein.
Applications Notes
Western blot (WB) analysis of CD155 polyclonal antibody at 1:10000 dilution Lane1:CT-26 whole cell lysate (30ug) Lane2:HepG2 whole cell lysate (10ug) Lane3:A549 whole cell lysate (10ug)
Host or Source
Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1140828-01 0.02 mg (E-Coli)
Recombinant Escherichia coli O127:H6 Elongation factor 4 (lepA)
Ask
View Details 
MBS1140828-02 0.02 mg (Yeast)
Recombinant Escherichia coli O127:H6 Elongation factor 4 (lepA)
Ask
View Details 
MBS1140828-03 0.1 mg (E-Coli)
Recombinant Escherichia coli O127:H6 Elongation factor 4 (lepA)
Ask
View Details 
MBS1140828-04 0.1 mg (Yeast)
Recombinant Escherichia coli O127:H6 Elongation factor 4 (lepA)
Ask
View Details MBS1140828-05 0.02 mg (Baculovirus)
Recombinant Escherichia coli O127:H6 Elongation factor 4 (lepA)
Ask
View Details MBS1140828-06 0.02 mg (Mammalian-Cell)
Recombinant Escherichia coli O127:H6 Elongation factor 4 (lepA)
Ask
View Details