CCRL2 polyclonal antibody

Product Specifications

Background

Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

C-C chemokine receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptor; CCRL2; CCR11, CCR6, CKRX, CRAM, HCR

Swiss Prot

O00421

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to Human CCRL2.

Conjugation

Unconjugated

Applications

Dilution

WB 1:500 - 1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 40 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CCRL2 polyclonal antibody detects endogenous levels of CCRL2 protein.

Applications Notes

Western blot (WB) analysis of CCRL2 polyclonal antibody at 1:500 dilution LaneA:A375 whole cell lysate (30ug) LaneB:H1688 whole cell lysate (30ug) LaneC:The Spleen tissue lysate of Mouse (30ug) LaneD:The Spleen tissue lysate of Rat (30ug)