CCRL2 polyclonal antibody
Product Specifications
Background
Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
C-C chemokine receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptor; CCRL2; CCR11, CCR6, CKRX, CRAM, HCR
Swiss Prot
O00421
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human CCRL2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CCRL2 polyclonal antibody detects endogenous levels of CCRL2 protein.
Applications Notes
Western blot (WB) analysis of CCRL2 polyclonal antibody at 1:500 dilution LaneA:A375 whole cell lysate (30ug) LaneB:H1688 whole cell lysate (30ug) LaneC:The Spleen tissue lysate of Mouse (30ug) LaneD:The Spleen tissue lysate of Rat (30ug)
Host or Source
Rabbit
Available Sizes
Curated Selection
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