Aggrecan polyclonal antibody
Product Specifications
Background
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ACAN; AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK; aggrecan
Swiss Prot
P16112
Reactivity
Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 420-575 of human Aggrecan (NP_037359.3) .
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 261 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Aggrecan polyclonal antibody detects endogenous levels of Aggrecan protein.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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