TRAF3 polyclonal antibody
Product Specifications
Background
TRAF1 and TRAF2 (for TNF receptor-associated factors 1 and 2, respectively) . Both function to form heterodimeric complexes and associate with the cytoplasmic domain of TNF-R2. A third member of this protein family, alternatively designated CD40 bp, CRAF1, LAP1 or TRAF3, has been identified and shown to associate with the cytoplasmic domain of CD40. The similarity between a specific region of TRAF3 with regions of TRAF1 and TRAF2 define a “TRAF-C” domain that is necessary and sufficient for CD40 binding and homodimerization.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
CD40 receptor-associated factor 1; CRAF1; CD40-binding protein; CD40BP; LMP1-associated protein; LAP1; CAP-1; TRAF3; 7187; TRAF3; 601896; Q13114; CAP-1; CD40bp; CRAF1; LAP1
Swiss Prot
Q13114
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic peptide derived from human TRAF3: 101-200/568
Conjugation
Unconjugated
Related Pathways
NF-kB Signaling, STING Signaling, Toll-like Receptor signaling, Death Receptor Signaling
Applications
WB ELISA IHC IF
Dilution
WB: 1:500-1:2000 ELISA: 1:5000-1:10000 IHC: 1:100-1:500 IF: 1:100-1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 62 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TRAF3 polyclonal antibody detects endogenous levels of TRAF3 protein.
Applications Notes
Sample:Spleen (Mouse) Lysate at 40 ug Primary: Anti-TRAF3 at 1/300 dilution
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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