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Mouse anti human collagen IV a3 Chain

Product Specifications

Background

Alport's syndrome, an inherited disease, shows absence or reduction of the a5 chain in the glomerular, tubular and bowman's capsular basement membranes. Normal human kidney has a1 (TV) to a6 (IV) chains in the renal basement membrance.

CAS Number

9007-83-4

Structure Composition

Appearance:Solution, Monoclonal antibodies were purified by affinity chromatography.0.02% ProClin 300 is added for preservation.

Immunogen

Synthetic peptides NC1 domain of type lV collagen.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

Monoclonal antibodies were prepared by the mouse splenocytes fusion method.

Modification

Unmodification

Storage Conditions

Store at 4°C.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

18G6-2 (mouse lgG1/kappa) is specific to NC1 domain of a5 (IV) .

Applications Notes

FITC fluorescence a3 chain is observed in the GBM and part of the TBM.

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

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