LSM4 polyclonal antibody
Product Specifications
Background
Sm and Sm-like (LSm) proteins form donut shaped heptameric complexes that are involved in various steps of RNA metabolism. Lsm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm4, also called U6 snRNA-associated Sm-like protein or Glycine-rich protein (GRP), binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm4 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1/2 and the exonuclease, Xm1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
U6 snRNA-associated Sm-like protein LSm4; Glycine-rich protein; GRP; LSM4
Swiss Prot
Q9Y4Z0
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to Human LSM4.
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 15 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LSM4 polyclonal antibody detects endogenous levels of LSM4 protein.
Applications Notes
Western blot analysis of LSm4 expression in K562 (A), NIH3T3 (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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