CD262 polyclonal antibody
Product Specifications
Background
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2; TRAIL receptor 2; TRAIL-R2; TNFRSF10B; DR5, KILLER, TRAILR2, TRICK2, ZTNFR9; UNQ160/PRO186
Swiss Prot
O14763
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human CD262.
Conjugation
Unconjugated
Related Pathways
Death Receptor Signaling
Applications
WB
Dilution
WB: 1:1000~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD262 polyclonal antibody detects endogenous levels of CD262protein.
Applications Notes
Western blot (WB) analysis of CD262 polyclonal antibody at 1:1000 dilution Lane1:Hela whole cell lysate (30ug) Lane2:A549 whole cell lysate (30ug) Lane3:The Heart tissue lysate of Mouse (30ug) Lane4:The Heart tissue lysate of Rat (30ug)
Host or Source
Rabbit
Available Sizes
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