CAPN6 monoclonal antibody
Product Specifications
Background
Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
CALPM; CANPX; Calpain-6; Calpain-like protease X-linked; Calpamodulin; CalpM
Swiss Prot
O35646
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human CAPN6. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000), FC (1/10 - 1/50)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 74 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of CAPN6 protein.
Applications Notes
Western blot analysis of CAPN6 expression in human placenta (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
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