FN3K monoclonal antibody
Product Specifications
Background
Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function (By similarity) . Also able to phosphorylate psicosamines and ribulosamines.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide.
Product Name Alternative
Fructosamine-3-kinase
Swiss Prot
Q9H479
Reactivity
Human
Immunogen
Recombinant fusion protein of human FN3K. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/4000)
Modification
Unmodification
Molecular Weight
~ 37 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of FN3K protein.
Applications Notes
Western blot analysis of FN3K expression in K562 (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
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