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CD273 monoclonal antibody

Product Specifications

Background

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .

CAS Number

9007-83-4

Structure Composition

Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

B7DC; CD273; PDCD1L2; PDL2; Programmed cell death 1 ligand 2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD273

Swiss Prot

Q9BQ51

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD273. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB (1/1000 - 1/4000), IHC (1/50 - 1/200)

Purity

This antibody is purified through a protein G column.

Modification

Unmodification

Molecular Weight

~ 55 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of CD273 protein.

Applications Notes

Western blot analysis of CD273 expression in Nontransfected 293T (A), Transfected PDL2transfected 293T (B) whole cell lysates.

Host or Source

Mouse

Available Sizes

Curated Selection

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