LYPD6B monoclonal antibody
Product Specifications
Background
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
CAS Number
9007-83-4
Structure Composition
Mouse IgG2b. Supplied in crude ascites with 0.01% sodium azide.
Product Name Alternative
Ly6/PLAUR domain-containing protein 6B
Swiss Prot
Q8NI32
Reactivity
Human, Mouse
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LYPD6B. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/2000)
Modification
Unmodification
Molecular Weight
~ 27 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of LYPD6B protein.
Applications Notes
Western blot analysis of LYPD6B expression in mouse stomach (A) whole cell lysates.
Host or Source
Mouse
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