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GNAS monoclonal antibody

Product Specifications

Background

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) . Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as Gnas isoforms.

CAS Number

9007-83-4

Structure Composition

Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.

Product Name Alternative

GNAS complex locus

Swiss Prot

Q6R0H7; P63094; Q9Z0F1

Reactivity

Mouse

Immunogen

KLH-conjugated synthetic peptide of human GNAS. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Modification

Unmodification

Molecular Weight

~ 50 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of GNAS protein.

Applications Notes

Western blot analysis of GNAS expression in mouse brain (A) whole cell lysates.

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

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