GNAS monoclonal antibody
Product Specifications
Background
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) . Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as Gnas isoforms.
CAS Number
9007-83-4
Structure Composition
Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.
Product Name Alternative
GNAS complex locus
Swiss Prot
Q6R0H7; P63094; Q9Z0F1
Reactivity
Mouse
Immunogen
KLH-conjugated synthetic peptide of human GNAS. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Modification
Unmodification
Molecular Weight
~ 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of GNAS protein.
Applications Notes
Western blot analysis of GNAS expression in mouse brain (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
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