MVP monoclonal antibody
Product Specifications
Background
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide.
Product Name Alternative
LRP; Major vault protein; MVP; Lung resistance-related protein
Swiss Prot
Q14764
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MVP. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Modification
Unmodification
Molecular Weight
~ 107 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of MVP protein.
Applications Notes
Western blot analysis of MVP expression in Hela (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
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