TLE4 monoclonal antibody
Product Specifications
Background
Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors, such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.
CAS Number
9007-83-4
Structure Composition
Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.
Product Name Alternative
KIAA1261; Transducin-like enhancer protein 4
Swiss Prot
Q04727
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TLE4. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
Wntβ catenin signaling
Applications
WB
Dilution
WB (1/500 - 1/1000)
Modification
Unmodification
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of TLE4 protein.
Applications Notes
Western blot analysis of TLE4 expression in NCIH460 (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
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