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PFKP monoclonal antibody

Product Specifications

Background

Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate in glycolysis. There are three isozymes: muscle-type, liver-type, and platelet-type. Platelet-type phosphofructokinase (PFKP) is expressed in various cell types. Research studies have shown that genetic variations in PFKP are associated with individuals born small for gestational age that are prone to obesity and diabetes later in adulthood.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

PFKF; 6-phosphofructokinase type C; 6-phosphofructokinase, platelet type; Phosphofructo-1-kinase isozyme C; PFK-C; Phosphofructokinase 1; Phosphohexokinase

Swiss Prot

Q01813

Reactivity

Human, Mouse, Monkey

Immunogen

Recombinant fusion protein of human PFKP. The exact sequence is proprietary.

Conjugation

Unconjugated

Related Pathways

Warburg Effect

Applications

WB

Dilution

WB (1/1000 - 1/2000)

Purity

This antibody is purified through a protein G column.

Modification

Unmodification

Molecular Weight

~ 80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of PFKP protein.

Applications Notes

Western blot analysis of PFKP expression in Hela (A), Jurkat (B), COS7 (C), mouse heart (D) whole cell lysates.

Host or Source

Mouse

Available Sizes

Curated Selection

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