PFKP monoclonal antibody
Product Specifications
Background
Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate in glycolysis. There are three isozymes: muscle-type, liver-type, and platelet-type. Platelet-type phosphofructokinase (PFKP) is expressed in various cell types. Research studies have shown that genetic variations in PFKP are associated with individuals born small for gestational age that are prone to obesity and diabetes later in adulthood.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
PFKF; 6-phosphofructokinase type C; 6-phosphofructokinase, platelet type; Phosphofructo-1-kinase isozyme C; PFK-C; Phosphofructokinase 1; Phosphohexokinase
Swiss Prot
Q01813
Reactivity
Human, Mouse, Monkey
Immunogen
Recombinant fusion protein of human PFKP. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
Warburg Effect
Applications
WB
Dilution
WB (1/1000 - 1/2000)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of PFKP protein.
Applications Notes
Western blot analysis of PFKP expression in Hela (A), Jurkat (B), COS7 (C), mouse heart (D) whole cell lysates.
Host or Source
Mouse
Available Sizes
Curated Selection
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