WNT4 monoclonal antibody
Product Specifications
Background
Ligand for members of the frizzled family of seven transmembrane receptors (Probable) . Plays an important role in the embryonic development of the urogenital tract and the lung .Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity) .Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries . Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary.Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity) .
CAS Number
9007-83-4
Structure Composition
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
Protein Wnt-4
Swiss Prot
P56705
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human WNT4. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/1000 - 1/2000)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of WNT4 protein.
Applications Notes
Western blot analysis of WNT4 expression in MCF7 (A), SKBR3 (B), MDAMB231 (C), Hela (D), mouse lung (E) whole cell lysates.
Host or Source
Mouse
Available Sizes
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