METAP1 monoclonal antibody
Product Specifications
Background
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) . Required for normal progression through the cell cycle.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
KIAA0094; Methionine aminopeptidase 1; MAP 1; MetAP 1; Peptidase M 1
Swiss Prot
P53582
Reactivity
Human
Immunogen
Recombinant fusion protein of human METAP1. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000), IHC (1/100 - 1/500)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 43 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of METAP1 protein.
Applications Notes
Western blot analysis of METAP1 expression in A549 (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
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