Alpha-synuclein monoclonal antibody

Product Specifications

Background

α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease .

CAS Number

9007-83-4

Structure Composition

Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP

Swiss Prot

P37840

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human Alpha-synuclein. The exact sequence is proprietary.

Conjugation

Unconjugated

Related Pathways

Dopamine Signaling in Parkinson\'s Disease Plathway.

Applications

Dilution

WB (1/500 - 1/1000)

Purity

This antibody is purified through a protein G column.

Modification

Unmodification

Molecular Weight

~ 18 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of Alpha-synuclein protein.

Applications Notes

Western blot analysis of Alpha-synuclein expression in human brain (A), mouse brain (B) whole cell lysates.

Host or Source

Mouse

Available Sizes

Curated Selection

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