IMPA1 monoclonal antibody
Product Specifications
Background
Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
IMPA; Inositol monophosphatase 1; IMP 1; IMPase 1; Inositol-1 (or 4) -monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1
Swiss Prot
P29218
Reactivity
Human
Immunogen
Recombinant fusion protein of human IMPA1. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 30 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of IMPA1 protein.
Applications Notes
Western blot analysis of IMPA1 expression in Jurkat (A), HL60 (B) whole cell lysates.
Host or Source
Mouse
Available Sizes
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