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CD55 monoclonal antibody

Product Specifications

Background

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

CR; DAF; Complement decay-accelerating factor; CD55

Swiss Prot

P08174

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD55. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Purity

This antibody is purified through a protein G column.

Modification

Unmodification

Molecular Weight

~ 78 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of CD55 protein.

Applications Notes

Western blot analysis of CD55 expression in Hela (A) whole cell lysates.

Host or Source

Mouse

Available Sizes

Curated Selection

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