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Kallikrein 3 monoclonal antibody

Product Specifications

Background

Kallikrein 3 (KLK3), also known as Prostate Specific Antigen (PSA), is a member of the glandular kallikrein subfamily of serine proteases. It is produced by prostate epithelial cells and is secreted into prostatic ducts. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase

Swiss Prot

P07288

Reactivity

Human

Immunogen

Purified recombinant fragment of human KLK3 expressed in E. Coli.

Conjugation

Unconjugated

Applications

WB, FC

Dilution

WB (1/500 - 1/1000), FC (1/50 - 1/100)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 34 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of Kallikrein 3 protein.

Applications Notes

Western blot analysis of Kallikrein 3 expression in human KLK3 recombinant protein (A) whole cell lysates.

Host or Source

Mouse

Available Sizes

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