NRF1 monoclonal antibody
Product Specifications
Background
Nuclear respiratory factor 1 (NRF1) was identified as a transcription activator for the gene encoding cytochrome c. It was later found to play a role in the nuclear control of mitochondrial function. PGC-1 induces the expression of NRF1 and NRF2. NRF1, along with the coactivator PGC-1, stimulates the promoter of mitochondrial transcription factor A, which regulates mitochondrial biogenensis and function.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal
Swiss Prot
Q16656
Reactivity
Human
Immunogen
Purified recombinant human NRF1 protein fragments expressed in E.coli
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of NRF1 protein.
Applications Notes
Western blot analysis of NRF1 expression in Hela (A), K562 (B), CEM (C), U2OS (D) whole cell lysates.
Host or Source
Mouse
Available Sizes
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