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NRF1 monoclonal antibody

Product Specifications

Background

Nuclear respiratory factor 1 (NRF1) was identified as a transcription activator for the gene encoding cytochrome c. It was later found to play a role in the nuclear control of mitochondrial function. PGC-1 induces the expression of NRF1 and NRF2. NRF1, along with the coactivator PGC-1, stimulates the promoter of mitochondrial transcription factor A, which regulates mitochondrial biogenensis and function.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal

Swiss Prot

Q16656

Reactivity

Human

Immunogen

Purified recombinant human NRF1 protein fragments expressed in E.coli

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 70 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of NRF1 protein.

Applications Notes

Western blot analysis of NRF1 expression in Hela (A), K562 (B), CEM (C), U2OS (D) whole cell lysates.

Host or Source

Mouse

Available Sizes

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