Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

FYN monoclonal antibody

Product Specifications

Background

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

Tyrosine-protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn

Swiss Prot

P06241

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Purified recombinant human Fyn protein fragments expressed in E.coli.

Conjugation

Unconjugated

Related Pathways

Tumor Angiogenesis, Regulation of Actin Dynamics, ErbB HER Signaling, Jak Stat : IL-6 Receptor Signaling, Inhibition of Apoptosis, Regulation of Microtubule Dynamics, PI3K AKT signaling, Wntβ catenin signaling

Applications

WB, IF/ICC

Dilution

WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 60 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of FYN protein.

Applications Notes

Western blot analysis of FYN expression in Hela (A), NIH3T3 (B), C6 (C), COS7 (D), CEM (E), Ramos (F), Jurkat (G) whole cell lysates.

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ESE1 (ELF3) (NM_001114309) Human Over-expression Lysate
LY426477 100 µg

ESE1 (ELF3) (NM_001114309) Human Over-expression Lysate

Sign In for Pricing
View Details
tert-Butyl Carbazate
TRC-B692170-50G 50 g

tert-Butyl Carbazate

Sign In for Pricing
View Details
FXYD6P3 Human Gene Knockout Kit (CRISPR)
KN415461 1 Kit

FXYD6P3 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
PRODH (Center) Rabbit Polyclonal Antibody
AP18160PU-N 400 µL

PRODH (Center) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Lanosterol
TRC-L174583-10MG 10 mg

Lanosterol

Sign In for Pricing
View Details
FAIM3 (FCMR) Rabbit Polyclonal Antibody
TA369117 100 µL

FAIM3 (FCMR) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details