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TBL1X monoclonal antibody

Product Specifications

Background

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units .Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Product Name Alternative

TBL1; F-box-like/WD repeat-containing protein TBL1X; SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked

Swiss Prot

O60907

Reactivity

Human

Immunogen

Purified recombinant human TBL1 protein fragments expressed in E.coli.

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 60 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of TBL1X protein.

Applications Notes

Western blot analysis of TBL1X expression in SW480 (A) whole cell lysates.

Host or Source

Mouse

Available Sizes

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