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NEK4 polyclonal antibody

Product Specifications

Background

Protein kinase that seems to act exclusively upon threonine residues (By similarity) . Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

STK2; Serine/threonine-protein kinase Nek4; Never in mitosis A-related kinase 4; NimA-related protein kinase 4; Serine/threonine-protein kinase 2; Serine/threonine-protein kinase NRK2

Swiss Prot

P51957

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NEK4. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 94 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of NEK4 protein.

Applications Notes

Western blot analysis of NEK4 expression in MCF7 (A), Myla2059 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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