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EIF5 polyclonal antibody

Product Specifications

Background

Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]) .

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

Eukaryotic translation initiation factor 5; eIF-5

Swiss Prot

P55010

Reactivity

Human, Mouse, Rat

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EIF5. The exact sequence is proprietary.

Conjugation

Unconjugated

Related Pathways

Translational Contral Regulation of elF2, Translational Contral Regulation of elF2

Applications

WB, IHC

Dilution

WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 49 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of EIF5 protein.

Applications Notes

Western blot analysis of EIF5 expression in mouse liver (A), mouse kidney (B), rat kidney (C) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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