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BCL2L12 polyclonal antibody

Product Specifications

Background

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2) . The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein

Swiss Prot

Q9HB09

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L12. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 36 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of BCL2L12 protein.

Applications Notes

Western blot analysis of BCL2L12 expression in K562 (A), HEK293T (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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