Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

KLHL3 polyclonal antibody

Product Specifications

Background

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron . The BCR (KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation . The BCR (KLHL3) complex also mediates ubiquitination and degradation of CLDN8, a tight-junction protein required for paracellular chloride transport in the kidney (By similarity) .

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

KIAA1129; Kelch-like protein 3

Swiss Prot

Q9UH77

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KLHL3. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 78 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of KLHL3 protein.

Applications Notes

Western blot analysis of KLHL3 expression in U87MG (A), HEK293T (B), Hela (C) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

TSSK6 Protein Vector (Rat) (pPB-C-His)
PV313446 500 ng

TSSK6 Protein Vector (Rat) (pPB-C-His)

Sign In for Pricing
View Details
GTF2A2 Recombinant Protein (Rat)
RP203912 100 µg

GTF2A2 Recombinant Protein (Rat)

Sign In for Pricing
View Details
PIEZO2 (Piezo-Type Mechanosensitive Ion Channel Component 2)
488647 100 µL

PIEZO2 (Piezo-Type Mechanosensitive Ion Channel Component 2)

Sign In for Pricing
View Details
Lentiviral mouse Aadacl2 shRNA (UAS) - Lentiviral mouse Aadacl2 shRNA (UAS, RFP) plasmid
GTR15293584 1 Vial

Lentiviral mouse Aadacl2 shRNA (UAS) - Lentiviral mouse Aadacl2 shRNA (UAS, RFP) plasmid

Sign In for Pricing
View Details
Mouse Procollagen III (PCIII) ELISA Kit
MBS2104909-01 24 Strip Well

Mouse Procollagen III (PCIII) ELISA Kit

Sign In for Pricing
View Details
Mouse Procollagen III (PCIII) ELISA Kit
MBS2104909-02 48 Well

Mouse Procollagen III (PCIII) ELISA Kit

Sign In for Pricing
View Details