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CLCN7 polyclonal antibody

Product Specifications

Background

Slowly voltage-gated channel mediating the exchange of chloride ions against protons.Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH .The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons .The presence of conserved gating glutamate residues is typical for family members that function as antiporters.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

H (+) /Cl (-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7

Swiss Prot

P51798

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CLCN7. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 110 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of CLCN7 protein.

Applications Notes

Western blot analysis of CLCN7 expression in HEK293T (A), MCF7 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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