Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DLC1 polyclonal antibody

Product Specifications

Background

Loss of expression of deleted in liver cancer 1 (DLC-1) protein correlates strongly with cancerous phenotype in a large number of human tissues, such as breast, liver, colon and prostate, and generally occurs due to genomic deletion or aberrant promotor methylation. The gene encoding DLC-1 maps to human chromasome 8p22, a region presumed to harbor tumor supressor genes based on its frequent mutation in a large number of cancers. DLC-1 localizes to the cytoplasm and restored expression leads to caspase-3 mediated apoptosis, and inhibition of cell growth and invasiveness.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

ARHGAP7; KIAA1723; STARD12; Rho GTPase-activating protein 7; Deleted in liver cancer 1 protein; DLC-1; HP protein; Rho-type GTPase-activating protein 7; START domain-containing protein 12; StARD12; StAR-related lipid transfer protein 12

Swiss Prot

Q96QB1

Reactivity

Human, Mouse, Rat

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human DLC1. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 175 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of DLC1 protein.

Applications Notes

Western blot analysis of DLC1 expression in C6 (A), CT26 (B), LOVO (C), HEK293T (D) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD157 polyclonal antibody
NCP0276P-01 50 µL

CD157 polyclonal antibody

Sign In for Pricing
View Details
CD157 polyclonal antibody
NCP0276P-02 100 µL

CD157 polyclonal antibody

Sign In for Pricing
View Details
Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)
MBS1230119-01 0.02 mg (E-Coli)

Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)

Sign In for Pricing
View Details
Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)
MBS1230119-02 0.02 mg (Yeast)

Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)

Sign In for Pricing
View Details
Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)
MBS1230119-03 0.1 mg (E-Coli)

Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)

Sign In for Pricing
View Details
Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)
MBS1230119-04 0.1 mg (Yeast)

Recombinant Equine herpesvirus 1 Uncharacterized gene 67 protein (IR6)

Sign In for Pricing
View Details