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Mimecan polyclonal antibody

Product Specifications

Background

The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGFβ. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TFGβ1 or TGFβ2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

OIF; SLRR3A; Mimecan; Osteoglycin; Osteoinductive factor; OIF

Swiss Prot

P20774

Reactivity

Human, Bovine

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Mimecan. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 34 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of Mimecan protein.

Applications Notes

Western blot analysis of Mimecan expression in SKOVCAR3 (A), PC3 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Curated Selection

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