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FOXH1 polyclonal antibody

Product Specifications

Background

Ranscriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element) .

CAS Number

9007-83-4

Structure Composition

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

FAST1; FAST2; Forkhead box protein H1; Forkhead activin signal transducer 1; Fast-1; hFAST-1; Forkhead activin signal transducer 2; Fast-2

Swiss Prot

O75593

Reactivity

Human, Bovine

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human FOXH1. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB (1/500 - 1/1000), IF/ICC (1/50 - 1/200)

Purity

The antibody was purified by immunogen affinity chromatography.

Modification

Unmodification

Molecular Weight

~ 47 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of FOXH1 protein.

Applications Notes

Western blot analysis of FOXH1 expression in SGC7901 (A), Myla2059 (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Curated Selection

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