Dengue virus Type I Nonstructural Protein 1 polyclonal antibody

Dengue (Den) is one of the most threatening mosquito-borne viral diseases of humans. It is widely spread in the tropical and subtropical areas of the world, and its incidence, in terms of morbidity and mortality, has increased dramatically over the past 20 years.The etiological agent belongs to the flavivirus genus of the family Flaviviridae. Flavi-viruses are enveloped, single-stranded, positive-sense RNA vi-ruses formed by three structural proteins. Protein C (capsid), cnclosing the genome, forms a nucleocapsid that is surrounded by a lipid bilayer in which are anchored proteins M (mem-brane) and E (envelope) .

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .