Heartland bandavirus Nucleocapsid Protein polyclonal antibody

Heartland virus (HRTV) is a recently described tick-borne phlebovirus. Phleboviruses are single-stranded RNA viruses in the family Bunyaviridae. The original two cases of HRTV disease were initially reported in adult males from Missouri. Both case-patients presented with a non-specific febrile illness with leukopenia and thrombocytopenia and history of tick exposure. They were initially diagnosed with ehrlichiosis for which they received doxycycline. The case-patients required hospitalization for approximately 11 days before being discharged to home where they eventually recovered. Subsequent field work identified the virus in Ambylommaamericanum ticks collected on one of the original patient’s farms and at a nearby site .

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .