Sicilian phlebovirus Nucleocapsid Protein polyclonal antibody
Product Specifications
Background
Sandfly fever Sicilian virus (SFSV) is one of the most widespread and frequently identified members of the genus Phlebovirus (order Bunyavirales, family Phenuiviridae) infecting humans. Being transmitted by Phlebotomus sandflies, SFSV causes a self-limiting, acute, often incapacitating febrile disease ("sandfly fever, " "Pappataci fever, " or "dog disease") that has been known since at least the beginning of the 20th century. Similarly to other pathogenic phleboviruses, SFSV suppresses the induction of the antiviral type I interferon (IFN) system in an NSs-dependent manner. SFSV NSs interfered with the TBK1-interferon regulatory factor 3 (IRF3) branch of the RIG-I signaling pathway but not with NF-κB activation.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Swiss Prot
EF201822.1
Reactivity
SFSV
Immunogen
Recombinant protein of SFSV.
Conjugation
Unconjugated
Applications
WB ELISA
Dilution
WB: 1:500~1:2000 ELISA: 1:5000~10000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Sicilian phlebovirus Nucleocapsid Protein polyclonal antibody detects endogenous levels of SFSV protein.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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