TSG101/VPS23 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
TSG10; VPS23; TSG101 / VPS23; TSG101
Swiss Prot
Q99816
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human TSG101/VPS23 (NP_006283.1) .
Conjugation
Unconjugated
Applications
IF/ICC
Dilution
IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Applications Notes
Immunofluorescence analysis of Jurkat cells using TSG101/VPS23 Rabbit pAb at dilution of 1:150 . Blue: DAPI for nuclear staining.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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