GSK3β polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
GSK3B; gsk-3β
Swiss Prot
P49841
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human GSK3β.
Conjugation
Unconjugated
Applications
WB IF IP
Dilution
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:50-1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 46 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GSK3β polyclonal antibody detects endogenous levels of GSK3β protein.
Applications Notes
Western blot (WB) analysis of GSK3β pAb at 1:500 dilution Lane1:PMVEC whole cell lysate (30ug) Lane2:3T3-L1 whole cell lysate (30ug) Lane3:U-87MG whole cell lysate (30ug) Lane4:HepG2 whole cell lysate (30ug) Lane5:HEK293T whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
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