FTO polyclonal antibody
Product Specifications
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
FTO; ALKBH9; BMIQ14; GDFD
Swiss Prot
Q9C0B1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human FTO (NP_001073901.1) .
Conjugation
Unconjugated
Applications
WB, IP
Dilution
WB,1:500 - 1:2000|IP,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
60KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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