PER2 polyclonal antibody

Product Specifications

Background

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

PER2; FASPS; FASPS1

Swiss Prot

O15055

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PER2 (NP_073728.1) .

Conjugation

Unconjugated

Applications

WB, IHC, ChIP

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:200|ChIP,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .