Phospho-FOXO3A-S294 polyclonal antibody

Product Specifications

Background

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

FOXO3; AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A; FoxO3a

Swiss Prot

O43524

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphorylated peptide around S294 of human FOXO3A (NP_001446.1) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:500 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .