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Phospho-NMDAR1-S890 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

GRIN1; GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1; NMDA 1

Swiss Prot

Q05586

Reactivity

Human, Rat

Immunogen

A synthetic phosphorylated peptide around S890 of human NMDAR1 (NP_015566.1) .

Conjugation

Unconjugated

Applications

WB

Dilution

WB,1:500 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Phosphorylated

Molecular Weight

140kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phosphorylated

Host or Source

Rabbit

Available Sizes

Curated Selection

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