Phospho-Vimentin-S39 polyclonal antibody

Product Specifications

Background

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CTRCT30; HEL113; Vimentin; VIM; vimentin

Swiss Prot

P08670

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphorylated peptide around S39 of human VIM (NP_003371.2) .

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .