Phospho-p90Rsk/RSK1/RPS6KA1-S380 polyclonal antibody

Product Specifications

Background

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

HU-1; MAPKAPK1A; RSK; RSK1; p90Rsk; RPS6KA1

Swiss Prot

Q15418

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphorylated peptide around S380 of human p90Rsk/RSK1/RPS6KA1 (NP_002944.2) .

Conjugation

Unconjugated

Applications

WB, IP

Dilution

WB,1:500 - 1:2000|IP,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .