Phospho-EGFR-Y1068 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA

Swiss Prot

P00533

Reactivity

Human, Mouse

Immunogen

A synthetic phosphorylated peptide around Y1068 of human EGFR (NP_005219.2) .

Conjugation

Unconjugated

Applications

WB, IP

Dilution

WB,1:1000 - 1:2000|IP,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .