DHX36 polyclonal antibody

Product Specifications

Background

This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA) . The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

DHX36; DDX36; G4R1; MLEL1; RHAU

Swiss Prot

Q9H2U1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human DHX36 (NP_065916.2) .

Conjugation

Unconjugated

Applications

WB, IP

Dilution

WB,1:200 - 1:2000|IP,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .