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TCF4/TCF7L2 polyclonal antibody

Product Specifications

Background

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

TCF-4; TCF4; TCF7L2

Swiss Prot

Q9NQB0

Reactivity

Human

Immunogen

A synthetic peptide of human TCF4/TCF7L2.

Conjugation

Unconjugated

Applications

WB IHC IP

Dilution

WB:1:500-1:1,000 IHC:1:50-1:100 IP:1:10-1:50

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 68 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

TCF4/TCF7L2 polyclonal antibody detects endogenous levels of TCF4/TCF7L2 protein.

Applications Notes

Western blot analysis of TCF4/TCF7L2 expression in K562 (A), Hela (B) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Curated Selection

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